Publications

Selected publications from the NADIS consortium

Delayed molecular aging, preservation of energy metabolism and enhanced exercise response in exercise-trained human muscle

Georges E. Janssens, Maria M. Trętowicz et al.

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The mitochondrial unfolded protein response in human microglia disrupts neuronal–glial communication and promotes senescence

Maria Jose Perez J et al.

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Human whole-blood NAD+ levels do not vary with age or lifestyle interventions

Maria M. Trętowicz et al.

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Therapeutic potential of dihydronicotinamide riboside (NRH) on obesity and glucose intolerance in mice

Marie Rumpler et al.

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Reduced Versus Oxidized NAD+ Precursors Drive Distinct Transcriptomic, Proteomic, and Metabolic Profiles in Hepatocytes

Kasper T. Vinten et al.

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Adapting health, economic and social policies to address population aging in China

Evandro F. Fang, Yuan Fang et al.

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NAD⁺ precursor supplementation in human ageing: clinical evidence and challenges

Kasper T. Vinten, Maria M. Trętowicz et al.

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Emerging strategies, applications and challenges of targeting NAD⁺ in the clinic

Jianying Zhang et al.

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Nicotinamide riboside first alleviates symptoms but later downregulates dopamine metabolism in proteasome inhibition mouse model of Parkinson’s disease

Giorgio Turconi et al.

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NAD⁺ repletion with niacin counteracts cancer cachexia

Marc Beltrà et al.

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Healthy aging and muscle function are positively associated with NAD⁺ abundance in humans

Georges E. Janssens et al.

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NAD⁺ to assess health in aging humans

Georges E. Janssens, Riekelt H. Houtkooper, Joris Hoeks

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NAD⁺ homeostasis in human health and disease

Rubén Zapata‐Pérez, Ronald J A Wanders, Clara D M van Karnebeek, Riekelt H Houtkooper

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Niacin Cures Systemic NAD⁺ Deficiency and Improves Muscle Performance in Adult-Onset Mitochondrial Myopathy

Eija Pirinen et al.

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NAD⁺ in Brain Aging and Neurodegenerative Disorders

Sofie Lautrup, David A. Sinclair, Mark P. Mattson, Evandro F. Fang

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The NAD⁺ Precursor Nicotinamide Riboside Rescues Mitochondrial Defects and Neuronal Loss in iPSC and Fly Models of Parkinson’s Disease

David C. Schöndorf et al.

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NAD⁺ Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus

Carles Cantó, Keir J. Menzies, Johan Auwerx

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Exploring the therapeutic space around NAD⁺

Riekelt H. Houtkooper, Johan Auwerx

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The NAD⁺ Precursor Nicotinamide Riboside Enhances Oxidative Metabolism and Protects against High-Fat Diet-Induced Obesity

Carles Cantó, Riekelt H. Houtkooper et al.

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The Secret Life of NAD⁺: An Old Metabolite Controlling New Metabolic Signaling Pathways

Riekelt H. Houtkooper, Carles Cantó, Ronald J. Wanders, Johan Auwerx

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AMPK regulates energy expenditure by modulating NAD⁺ metabolism and SIRT1 activity

Carles Cantó et al.

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